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Alpha2EQ: addressing equine lameness at the source.

Alpha2EQ: an orthobiologic targeting equine inflammation and lameness.

Alpha2EQ: an orthobiologic targeting equine inflammation and lameness.

Alpha2EQ, the potent biological anti-inflammatory molecule addressing equine lameness, joint inflammation and soft tissue injury at the source.

How/Why Alpha2EQ stands out

What is Alpha2EQ?

Alpha2EQ is an orthobiologic, which means it is composed of biological, naturally occurring substances to help improve the body’s own healing process. Using a sample of your horse’s own blood, your veterinarian will use the patent pending AlphaActive process to separate the plasma, then filter and isolate the protein alpha-2-marcroglobulin.

This protein is the key factor. When injected or applied to areas of inflammation, alpha-2-macroglobulin removes the damage-causing enzymes to help improve the healing process and protect against further damage.



Orthobiologics: What are they and why are they important?

Orthobiologics are derived from natural substances found in the body. They can be used to promote healing. When trauma occurs to joints and soft tissue, it triggers the inflammatory cascade. This includes the release of protease enzymes and pro-inflammatory cytokines. Left unchecked, proteases and cytokines may cause more tissue damage.



Alpha-2-macroglobulin: A potent anti-inflammatory molecule

Alpha-2-macroglobulin (a2M) is a naturally occurring protein within the blood. The molecule has the ability to block the destructive effect of these enzymes by capturing them in a “trap” when the enzymes cleave the molecule’s amino acid “bait” region. a2M has a unique multimodal mechanism of action: non-specific protease inhibition, gene regulation, as well as cytokine and growth factor modulation.




Alpha2EQ: Targeting injury at the source

Alpha2EQ is powered by an advanced, patent pending AlphaActive filtration process. This highly improved process filters plasma proteins from the equine patient’s own blood, removing harmful proteins that can remain in other autologous plasma products leaving an isolated alpha-2-macroglobulin product.

In just a few simple steps, utilizing the AlphaActive filtration process, Alpha2EQ delivers a reliable product to target injury at the source.

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